Below is a table adapted from the U.S. Food and Drug Administration’s Pharmacogenomic Biomarkers in Drug Labels. All drugs listed below include PGx information in their drug labels. We have included the drug name, the associated PGx Biomarker, and a link to professional positional statements and clinical guidelines.
| Brand Name (alphabetized by Generic Name) | Biomarker | Professional Position Statements & Clinical Guidelines |
| Ziagen®(Abacavir) | HLA-B*5701 | CPIC Guidelines (2014)
HIV Medicine Association of the Infectious Diseases Society of America (2009) |
| Kadcyla®(Ado-Trastuzumab Emtansine) | ERBB2 | No clinical guidelines available. |
| Gilotrif®(Afatinib) | EGFR | No clinical guidelines available. |
| Elavil®(Amitriptyline) | CYP2D6 | CPIC Guidelines (2013) |
| Arimidex®(Anastrozole) | ESR1, PGR | No clinical guidelines available. |
| Abilify®(Aripiprazole) | CYP2D6 | No clinical guidelines available. |
| Trisenox®(Arsenic Trioxide) | PML/RARα | No clinical guidelines available. |
| Strattera®(Atomoxetine) | CYP2D6 | No clinical guidelines available. |
| Lipitor®(Atorvastatin) | LDL Receptor | No clinical guidelines available. |
| Imuran®(Azathioprine) | TPMT | CPIC Guidelines (2011) |
| Victrelis®(Boceprevir) | IL28B | Dept of Veterans Affairs Hep C Resource Center Program & the National Hep C Program Office |
| Adcetris®(Brentuximab Vedotin) | CD30 | No clinical guidelines available. |
| Busulfex®(Busulfan) | Ph Chromosome | No clinical guidelines available. |
| Xeloda®(Capecitabine) | DPD | CPIC Guidelines (2013) |
| Tegretol®(Carbamazepine) | HLA-B*1502 | CPIC Guidelines (2013) |
| Carbaglu®(Carglumic Acid) | NAGS | No clinical guidelines available |
| Soma®(Carisoprodol) | CYP2C19 | No clinical guidelines available. |
| Coreg®(Carvedilol) | CYP2D6 | No clinical guidelines available. |
| Celebrex®(Celecoxib) | CYP2C9 | No clinical guidelines available. |
| Erbitux®(Cetuximab) | EGFR, KRAS | National Comprehensive Cancer Network (2014) |
| Evoxac®(Cevimeline) | CYP2D6 | No clinical guidelines available. |
| Aralen®(Chloroquine) | G6PD | No clinical guidelines available. |
| Diabinese®(Chlorpropamide) | G6PD | No clinical guidelines available. |
| Platinol®(Cisplatin) | TPMT | CPIC Guidelines (2011) |
| Celexa®(Citalopram) | CYP219, CYPD6 | No clinical guidelines available. |
| Onfi®(Clobazam) | CYP2C19 | No clinical guidelines available. |
| Clomid® (Clomiphene) | Rh genotype | No clinical guidelines available. |
| Anafranil®(Clomipramine) | CYPD2D6 | CPIC Guidelines (2013) |
| Plavix® (Clopidogrel) | CYP2C19 | CPIC Guidelines (2013)
American College of Cardiology Foundation/American Heart Association (2012) |
| Clozaril®(Clozapine) | CYP2D6 | No clinical guidelines available. |
| Codeine® (Codeine) | CYP2D6 | CPIC Guidelines (2014) |
| Xalkori®(Crizotinib) | ALK | No clinical guidelines available. |
| Tafinlar®(Dabrafenib) | BRAF G6PD |
No clinical guidelines available. |
| Aczone®(Dapsone) | G6PD | No clinical guidelines available. |
| Sprycel®(Dasatinib) | Ph Chromosome | No clinical guidelines available. |
| Ontak®(Denileukin Diftitox) | CD25 | No clinical guidelines available. |
| Norpramin®(Desipramine) | CPY2D6 | CPIC Guidelines (2013) |
| Dexilant® (Dexlansoprazole) | CYP2C19 CYP1A2 |
No clinical guidelines available. |
| Nuedexta®(Dextromethorphan and Quinidine) | CYP2D6 | No clinical guidelines available. |
| Valium® (Diazepam) | CYP2C19 | No clinical guidelines available. |
| Silenor®(Doxepin) | CYP2D6 | CPIC Guidelines (2013) |
| Yaz® (Drospirenone and Ethinly Estradiol) | CYP2C19 | No clinical guidelines available. |
| Promacta®(Eltrombopag) | 5F, SERPINC1 | No clinical guidelines available. |
| Tarceva®(Erlotinib) | EGFR | No clinical guidelines available. |
| Nexium® (Esomeprazole) | CYP2C19 | No clinical guidelines available. |
| Afinitor®(Everolimus) | ER&PgR receptor | No clinical guidelines available. |
| Aromasin®(Exemestane) | ER&PgR receptor | No clinical guidelines available. |
| Carac®; Efudex®; Fluoroplex®(Fluorouracil) | DPD | CPIC Guidelines (2013) |
| Prozac®(Fluoxetine) | CYP2D6 | No clinical guidelines available. |
| Symbyax®(Fluoxetine and Olanzapine) | CYP2D6 | No clinical guidelines available. |
| Ansaid® (Flurbiprofen) | CYP2C9 | No clinical guidelines available. |
| Luvox® CR(Fluvoxamine) | CYP2D6 | No clinical guidelines available. |
| Faslodex®(Fulvestrant) | ER receptor | No clinical guidelines available. |
| Razadyne®(Galantamine) | CYP2D6 | No clinical guidelines available. |
| Amaryl®(Glimepiride) | G6PD | No clinical guidelines available. |
| Glucotrol®(Glipizide) | G6PD | No clinical guidelines available. |
| Diabeta® Glynase®(Glyburide) |
G6PD | No clinical guidelines available. |
| Iressa®(Gefitinib) | EGFR | No clinical guidelines available. |
| Fanapt®(Iloperidone) | CYP2D6 | No clinical guidelines available. |
| Gleevec®(Imatinib) | C-Kit, Ph Chromosome, PDGFR,FIP1L1-PDGFRα | No clinical guidelines available. |
| Tofranil® (Imipramine) | CYP2D6 | CPIC Guidelines (2013) |
| Arcapta® Neohaler®(Indacaterol) | UGT1A1 | No clinical guidelines available. |
| Camptosar®(Irinotecan) | UGT1A1 | No clinical guidelines available. |
| BiDil®(Isosorbide and Hydralazine) | NAT1, NAT2 | No clinical guidelines available. |
| Kalydeco®(Ivacaftor) | CFTR (G551D) | CPIC Guidelines (2014) |
| Prevacid®(Lansoprazole) | CYP2C19 | No clinical guidelines available. |
| Tykerb®(Lapatinib) | HER2/neu | No clinical guidelines available. |
| Revlimid®(lenalidomide) | Chromosome 5q | No clinical guidelines available. |
| Femara®(letrozole) | ER&PgR receptor | No clinical guidelines available. |
| Juxtapid®(Lomitapide) | LDLR | No clinical guidelines available. |
| Sulfamylon®(Mafenide) | G6PD | No clinical guidelines available. |
| Selzentry®(Maraviroc) | CCR5 | HIV Medicine Association of the Infectious Disease Society of America (2009) |
| Purinethol®(Mercaptopurine) | TPMT | CPIC Guidelines (2013) |
| Methylene Blue(Methylene Blue) | G6PD | No clinical guidelines available. |
| Reglan®(Metoclopramide) | CYB5R1-4 | No clinical guidelines available. |
| Lopressor®(Metoprolol) | CYP2D6 | No clinical guidelines available. |
| Kynamro®(Mipomersen) | LDLR | No clinical guidelines available. |
| Provigil®(Modafinil) | CYP2D6 | No clinical guidelines available. |
| Myfortic®(Mycophenolic Acid) | HGPRT | No clinical guidelines available. |
| NegGram®(Nalidixic Acid) | G6PD | No clinical guidelines available. |
| Serzone® (Nefazodone) | CYP2D6 | No clinical guidelines available. |
| Tasigna®(Nilotinib) | Ph Chromosome, UGT1A1 | No clinical guidelines available. |
| Furadantin®(Nitrofurantoin) | G6PD | No clinical guidelines available. |
| Pamelor®(Nortriptyline) | CYP2D6 | CPIC Guidelines (2013) |
| Gazyva®(Obinutuzumab) | CD20 Antigen | No clinical guidelines available. |
| Arzerra®(Ofatumumab) | CD20 Antigen | No clinical guidelines available. |
| Synribo®(Omacetaxine) | BCR/ABL1 | No clinical guidelines available. |
| Prilosec®(Omeprazole) | CYP2C19 | No clinical guidelines available. |
| Vectibix®(Panitumumab) | KRAS, EGFR | National Comprehensive Cancer Network (2014) |
| Protonix®(Pantoprazole) | CYP2C19 | No clinical guidelines available. |
| MoviPrep®(PEG-3350) | G6PD | No clinical guidelines available. |
| Paxil®(Paroxetine) | CYP2D6 | No clinical guidelines available. |
| PegIntron®(Peginterferon Alfa-2b) | IL28B | Dept of Veterans Affairs Hep C Resource Center Program & National Hep C Program Office (2012) |
| Krystexxa®(Pegloticase) | G6PD | No clinical guidelines available. |
| Trilafon® (Perphenazine) | CYP2D6 | No clinical guidelines available. |
| Perjeta® (Pertuzumab) | HER2/neu | No clinical guidelines available. |
| Dilantin®(Phenytoin) | HLA-B*1502 | No clinical guidelines available. |
| Orap®(Pimozide) | CYP2D6 | No clinical guidelines available. |
| Iclusig®(Ponatinib) | BCR-ABLBCR/ABL1 | No clinical guidelines available. |
| Effient®(Prasugrel) | CYP2C19 | American College of Cardiology Foundation (2011) |
| Pravachol®(Pravastatin) | ApoE2 | No clinical guidelines available. |
| Primaquine(Primaquine) | G6PD | No clinical guidelines available. |
| Rythmol SR®(Propafenone) | CYP2D6 | No clinical guidelines available. |
| Inderal®(Propranolol) | CYP2D6 | No clinical guidelines available. |
| Vivactil®(Protriptyline) | CYP2D6 | No clinical guidelines available. |
| Quinidine®(Quinidine) | CYP2D6 | No clinical guidelines available. |
| Qualaquin®(Quinine Sulfate) | G6PD | No clinical guidelines available. |
| Aciphex®(Rabeprazole) | CYP2C19 | No clinical guidelines available. |
| Elitek®(Rasburicase) | G6PD | No clinical guidelines available. |
| Rifater®(Rifamipin, Isoniazid and Pyrazinamide) | NAT1, NAT2 | No clinical guidelines available. |
| Risperda®(Risperidone) | CYP2D6 | No clinical guidelines available. |
| Rituxan®(Rituximab) | CD20 Antigen | No clinical guidelines available. |
| Crestor®(Rosuvastatin) | LDLR | No clinical guidelines available. |
| Olysio®(Simeprevir) | IL28B | No clinical guidelines available. |
| Zocor®(Simvastatin) ****Not in FDA Label |
SLCO1B1 | American College of Cardiology Foundation (2011)CPIC Guidelines (2014) |
| Sodium Nitrate(Sodium Nitrate) | G6PD | No clinical guidelines available. |
| Sovaldi(Sofosbuvir) | IL28B | No clinical guidelines available. |
| Chemet®(Succimer) | G6PD | No clinical guidelines available. |
| Bactrim®(Sulfamethoxazole and Trimethoprim) | G6PD | No clinical guidelines available. |
| Nolvadex® (Tamoxifen) | ER Receptor | No clinical guidelines available. |
| Incivek®(Telaprevir) | IL28B | Dept of Veterans Affairs Hep C Resource Center Program and the National Hep C Program Office (2012) |
| Lamisil® (Terbinafine) | CYP2D6 | No clinical guidelines available. |
| Xenazine®(Tetrabenazine) | CYP2D6 | No clinical guidelines available. |
| Tabloid®(Thioguanine) | TPMT | CPIC Guidelines (2011) |
| Mellaril® (Thioridazine) | CYP2D6 | CPIC Guidelines (2013) |
| Brilinta®(Ticagrelor) | CYP3A4, CYP2C19 |
American College of Cardiology Foundation (2011) |
| Detrol® (Tolterodine) | CYP2D6 | No clinical guidelines available. |
| Bexxar®(Tositumomab) | CD20 Antigen | No clinical guidelines available. |
| Ultram®(Tramadol) | CYP2D6 | No clinical guidelines available. |
| Mekinist®(Trametinib) | BRAF | No clinical guidelines available. |
| Herceptin®(Trastuzumab) | HER2/neu | No clinical guidelines available. |
| Vesanoid®(Tretinoin) | PML/RARα | No clinical guidelines available. |
| Surmontil®(Trimipramine) | CYP2D6 | CPIC Guidelines (2013) |
| Stavzor®(Valproic Acid) | UCD (NAGS,CPS,ASS,OTC,ASL,ARG) | No clinical guidelines available. |
| Zelboraf®(Vemurafenib) | BRAF | No clinical guidelines available. |
| Effexor®(Venlafaxine) | CYP2D6 | No clinical guidelines available. |
| Vfend®(Voriconazole) | CYP2C9 | No clinical guidelines available. |
| Brintellix®(Vortioxetine) | CYP2D6 | No clinical guidelines available. |
| Coumadin®(Warfarin) | CYP2C9, VKORC1 | CPIC Guidelines (2011)American College of Chest Physicians (2008) |
last updated August 20, 2014
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